HIGHLIGHTS
- who: Enyi Zhu from the Sunway University, Malaysia have published the paper: Targeting NK-1R attenuates renal fibrosis via modulating inflammatory responses and cell fate in chronic kidney disease, in the Journal: (JOURNAL)
- what: The 2-DDCt approach was implemented to determine gene levels, with b-actin as a reference. In the present study, as outlined in Figure 8, the authors identified that SP/NK-1R axis activation, arising from elevated SP and NK-1R levels upon injury, could augment renal cell apoptosis, G2/M arrest, proinflammatory/profibrogenic factors production, resulting in progressive renal fibrosis . . .
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