Risk stratification based on dna damage-repair-related signature reflects the microenvironmental feature, metabolic status and therapeutic response of breast cancer

HIGHLIGHTS

SUMMARY

    As the most commonly diagnosed malignancy globally, breast cancer (BRCA) has become a major driver of cancer-related deaths in women. ACTL6A was positively correlated with follicular helper T_cells, activated CD4+ memory T_cells, M1 macrophages and M0 macrophages, while it was negatively correlated with resting mast cells. The three progression-related DRGs, GNPNAT1, MORF4L2 and VAV3, consistently correlated negatively with CD8+ T_cells and positively with M2 macrophages. TANK expression was positively associated with multiple T_cell subtypes (CD8+ T_cells, activated CD4+ T_cells, etc.) except for Treg. Differences in TIDE scores (D), IFN-gamma scores (E . . .

     

    Logo ScioWire Beta black

    If you want to have access to all the content you need to log in!

    Thanks :)

    If you don't have an account, you can create one here.

     

Scroll to Top

Add A Knowledge Base Question !

+ = Verify Human or Spambot ?