Adam10 gene variants in ad patients and their relationship to csf protein levels

HIGHLIGHTS

• who: Pablo Agu00fcero-Rabes and collaborators from the Department of Neurology, Fundaciu00f3n Jimu00e9nez Du00edaz, Madrid, Spain Instituto de Neurociencias de Alicante, Universidad Miguel Hernu00e1ndez-CSIC, Alicante, Spain have published the research work: ADAM10 Gene Variants in AD Patients and Their Relationship to CSF Protein Levels, in the Journal: (JOURNAL)
• what: The authors examine the hypothesis that certain ADAM10 variants could increase the risk of AD by conferring earlier age-related downregulation of u03b1-secretase, in opposition with other variants capable of maintaining high levels/activity of u03b1-secretase at advanced ages. The authors analyzed ADAM10 . . .
  

   

  

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