Lack of aplp1 leads to subtle alterations in neuronal morphology but does not affect learning and memory

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  • who: ufeffUlrike C.ufeff ufeffMu00fcllerufeff from the University Medical Center Gu00f6ttingen, Germany have published the paper: Lack of APLP1 leads to subtle alterations in neuronal morphology but does not affect learning and memory, in the Journal: (JOURNAL)
  • what: At the behavioral level the authors report reduced grip strength and impaired locomotor activity, whereas no significant deficits were found in cognitive tasks, consistent with normal synaptic plasticity.
  • how: The authors studied neuronal morphology in the hippocampus of APLP1-KO mice examined basal synaptic transmission and synaptic plasticity at the CA3/CA1 pathway performed a . . .

     

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