Nadph oxidase 4: a potential therapeutic target of malignancy

HIGHLIGHTS

  • who: NOX and colleagues from the University of Texas MD Anderson Cancer Center, United States have published the article: NADPH Oxidase 4: A Potential Therapeutic Target of Malignancy, in the Journal: (JOURNAL)

SUMMARY

    Various mechanisms have been reported to regulate NOXs activity including post-translational modifications, lipids, calcium level, etc (Rossary et_al, 2007; Brandes et_al, 2014b; Douda et_al, 2015). NOXs also function as reactive oxygen species- (ROS-) producing enzymes to regulate a series of biological function, comprising redox-dependent signaling pathways, oxygen sensor, metabolic reprograming, and immune defense (Bedard and Krause, 2007; Leto . . .

     

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