HIGHLIGHTS
- who: Sara Gomes from the Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, University of, San Sebastiu00e1n, Spain have published the Article: Elevated urine BMP phospholipids in LRRK2 and VPS35 mutation carriers with and without Parkinsonu2019s disease, in the Journal: Neurology, Queen of 22/Nov/2022
- what: The authors provide confirmation that urine BMP isoforms are robustly elevated in carriers of the LRRK2 G2019S mutation and provide first time evidence that urine BMPs are also elevated in LRRK2 R1441G/C and VPS35 D620N mutation carriers, consistent with shared biological pathways involved in endolysosomal trafficking.
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