Inducible apelin receptor knockdown reduces differentiation efficiency and contractility of hesc-derived cardiomyocytes

HIGHLIGHTS

  • who: Robyn G.C. Macrae from the Experimental Medicine and Immunotherapeutics, University of Cambridge, Addenbrooke`s Hospital, Level, Addenbrooke`s Centre for Clinical Investigation, Box, Cambridge , QQ, USA have published the paper: Inducible apelin receptor knockdown reduces differentiation efficiency and contractility of hESC-derived cardiomyocytes, in the Journal: (JOURNAL) of 17/Dec/2021
  • what: The authors report that early apelin receptor knockdown throughout differu00ad entiation from hESC to hESC-CM, has a significant impact on phenotype reducing cardiomyocyte differentiation efficiency and increasing the number of fibroblasts, and functionally prolongs voltage signalling. The authors show that . . .

     

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