HIGHLIGHTS
- who: Angewandte and colleagues from the (UNIVERSITY) have published the article: Rational Design of a Facially Coordinating P,N,N Ligand for Manganeseu2010Catalysed Enantioselective Hydrogenation of Cyclic Ketones, in the Journal: (JOURNAL)
- what: The authors show how DFT calculations of the catalytic cycle have been found to be robust enough to enable in silico evaluation of substrates, and report a new catalyst that gives high enantioselectivity for a range of important substrates. The authors show that this rational-design approach has been highly successful and offers solutions to some unresolved challenges in earth abundant metal . . .
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