Engineering yeast mitochondrial metabolism for 3-hydroxypropionate production

HIGHLIGHTS

  • who: Yiming Zhang from the (UNIVERSITY) have published the paper: Engineering yeast mitochondrial metabolism for 3-hydroxypropionate production, in the Journal: (JOURNAL)
  • what: The authors explored the potential for production of 3-hydroxypropionate (3-HP) and performed the cofactor and flux control at the acetyl-CoA node to maximize 3-HP synthesis. In this study the mitochondrion is reported as an attractive compartment for 3-HP production. The work gains a better understanding for harnessing the yeast mitochondrion for synthesis of acetyl-CoA derived biochemicals, especially those with NADPH as a cofactor.
  • how . . .

     

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