HIGHLIGHTS
- who: Rita Bardoni from the (Neuro-Dol), France University of Auvergne, France have published the paper: 5-HT7 Receptors Regulate Excitatory-Inhibitory Balance in Mouse Spinal Cord Dorsal Horn, in the Journal: (JOURNAL)
- what: This study has investigated the modulatory action exerted by 5HT7 Rs on dorsal horn synaptic transmission. The study showed that LP-211 is particularly effective in increasing the excitability of tonic firing neurons, which mainly correspond to inhibitory interneurons (Daniele and MacDermott, 2009; Yasaka et_al, 2010; Hughes et_al, 2012).
- how: In the experiments the authors used the compound LP . . .
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