Peptides derived from hookworm anti-inflammatory proteins suppress inducible colitis in mice and inflammatory cytokine production by human cells

HIGHLIGHTS

  • who: Alex Loukas and Norelle L. Daly from the Shahid Beheshti University of Medical Sciences, Iran have published the paper: Peptides derived from hookworm anti-inflammatory proteins suppress inducible colitis in mice and inflammatory cytokine production by human cells, in the Journal: (JOURNAL)
  • how: The authors identified a small helical region conserved amongst these hookworm proteins which can alleviate symptoms in a chemically induced mouse model of colitis and suppress cytokine secretion by human peripheral blood mononuclear cells in_vitro. All animal experiments were conducted in at least duplicate on different days to ensure reproducibility of . . .

     

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