High mobility group box 1 (hmgb1): potential target in sepsis-associated encephalopathy

HIGHLIGHTS

  • who: Bram DeWulf and collaborators from the Department of Anesthesia-Critical Care, AZ Sint-Jan Brugge Oostende AV, Bruges, Department of Anesthesia, Antwerp University Hospital (UZA), Edegem, Sorbonne University, Assistance Publique-Hu00f4pitaux de Paris, Paris, France have published the research: High Mobility Group Box 1 (HMGB1): Potential Target in Sepsis-Associated Encephalopathy, in the Journal: Cells 2023, 1088 of 29/03/2023
  • how: This review describes inflammatory cascades implicating and strategies for its use to mitigate sepsis-induced encephalopathy. Multiple experimental interventions have shown promising results in modulating microglial activity including minocycline ketamine cholinergic inhibition . . .

     

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