Inhibition of bet proteins regulates fc receptor function and reduces inflammation in rheumatoid arthritis

HIGHLIGHTS

  • who: Divya Shankar and colleagues from the College of Medicine, The Ohio State University, Columbus, OH, USA have published the article: Inhibition of BET Proteins Regulates Fc Receptor Function and Reduces Inflammation in Rheumatoid Arthritis, in the Journal: (JOURNAL) of 30/03/2023
  • what: Epigenetic DNA modifications are of great importance to modify the expression of proteins regulating cellular processes such as inflammation.
  • how: Showed that treatment with PLX51107 significantly downregulated Fcu03b3RIIa Fcu03b3RIIb and Fcu03b3RIIIa mRNA expression . Showed that both phagocytosis and production the potently showed that both phagocytosis and production of the . . .

     

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