Targeted locus amplification to develop robust patient-specific assays for liquid biopsies in pediatric solid tumors

HIGHLIGHTS

  • who: Lieke M. J. van Zogchel from the United States University Hospital Rostock, Germany have published the research work: Targeted locus amplification to develop robust patient-specific assays for liquid biopsies in pediatric solid tumors, in the Journal: (JOURNAL)
  • what: In this report, the authors investigate the possibility of designing patient-specific assays for cell free tumor DNA detection in patients with neuroblastoma, rhabdomyosarcoma and Ewing sarcoma, using TLA/TLC - based breakpoint sequences. These methods still require the use of bone marrow, and the potential for response monitoring with this approach has not been shown . . .

     

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