Effects of cannabidiol on anandamide levels in individuals with cannabis use disorder: findings from a randomised clinical trial for the treatment of cannabis use disorder

HIGHLIGHTS

• who: Daniel Ying-Heng Hua from the A randomised, double-blind, placebo-controlled phase, a clinical trial was conducted to investigate CBD as a treatment for cannabis use disorderThe full methodology of this trial, including randomisation and blinding, has been reported previously [14]. This was a phase, a trial using a two-stage adaptive Bayesian dose-finding design, meaning that multiple dosages were used in order to statistically analyse the most and least efficacious dosage at mid-trial (stage, ) and end of trial (stage, ). Least efficacious dosages were eliminated at stage , so that subsequently recruited participants could . . .
  

   

  

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