Molecular mechanism underlying the increased risk of colorectal cancer metastasis caused by single nucleotide polymorphisms in li-cadherin gene

HIGHLIGHTS

• who: Anna Yui from the DepartmentThe University of Tokyo, Tokyo, Japan have published the article: Molecular mechanism underlying the increased risk of colorectal cancer metastasis caused by single nucleotide polymorphisms in LI-cadherin gene, in the Journal: Scientific Reports Scientific Reports
• what: Collectively, as a mechanism of how SNPs in the LI-cadherin gene increase the risk of colorectal cancer metastasis, the authors propose the mechanism shown in Fig 7.
• how: Both CD and DSC results indicated that the mutation of Lys115 to Glu did not significantly alter the folding of EC1-4 . . .
  

   

  

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