HIGHLIGHTS
- who: Yu-Tzu Chan from the (UNIVERSITY) have published the Article: The interplay between IGF-1R signaling and Hippo-YAP in breast cancer stem cells, in the Journal: (JOURNAL)
- what: The authors used breast cancer PDX models to show that IGF-1R signaling regulates YAP expression and its localization.
- future: There was no direct evidence supporting regulation of IGF-1 or IGF-2 by YAP which awaits future studies.
SUMMARY
Cancer stem_cells (CSCs) represent a small population of cancer cells with the capacities of self-renewal and differentiation. Clinically . . .
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