Structural basis of centromeric cohesion protection

HIGHLIGHTS

• who: Alberto Garcamp#x000ED and a-Nieto from the Centromeric cohesion have published the paper: Structural basis of centromeric cohesion protection, in the Journal: (JOURNAL) of 15/03/2023

SUMMARY

The authors were able to obtain crystals with a SGO1 peptide spanning amino_acids 331-341 containing the YxF motif but not with an extended peptide spanning amino_acids 331-349 containing pT346. Briefly, the binding pocket for F337 of SGO1 contains amino_acids S334, I337 and L341 from SCC1 and Y297 and W334 from SA2 (Fig 1c and Extended Data Fig 1d). A model calculated . . .

 



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