Human umbilical cord mesenchymal stem cell-derived tgfbi attenuates streptozotocin-induced type 1 diabetes mellitus by inhibiting t-cell proliferation

HIGHLIGHTS

• who: Chushan Wu from the (UNIVERSITY) have published the research work: Human umbilical cord mesenchymal stem cell-derived TGFBI attenuates streptozotocin-induced type 1 diabetes mellitus by inhibiting T-cell proliferation, in the Journal: (JOURNAL)
• what: The authors showed that hUC-MSCs knockdown of TGFBI reduced their ability to inhibit T-cell proliferation and impaired therapeutic effects in T1DM mice.
• how: The data showed that transforming growth factor beta-induced gene (TGFBI) was highly expressed in MSCs obtained from human umbilical cord. Flow cytometry Flow cytometric analysis was performed on the FACScalibur flow . . .
  

   

  

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