Stiffening of circumferential f-actin bands correlates with regenerative failure and may act as a biomechanical brake in the mammalian inner ear

HIGHLIGHTS

• who: Jeffrey T. Corwin from the University of Mississippi Medical Center, United States have published the Article: Stiffening of Circumferential F-Actin Bands Correlates With Regenerative Failure and May Act as a Biomechanical Brake in the Mammalian Inner Ear, in the Journal: (JOURNAL)
• how: For PFT-AFM imaging the authors used a driving frequency of 500 Hz and drive amplitudes of 500 to 650 nm.
• future: Studies are required to investigate whether mouse models that have enhanced regenerative capacity have SCs with thinner F-actin bands greater compliance and heightened YAP-TEAD signaling . . .
  

   

  

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