Technical considerations in pcr-based assay design for diagnostic dna methylation cancer biomarkers

HIGHLIGHTS

  • who: Maartje Massen from the (UNIVERSITY) have published the article: Technical considerations in PCR-based assay design for diagnostic DNA methylation cancer biomarkers, in the Journal: (JOURNAL)
  • what: Dataset characteristics Here, the authors provided an overview of the studied genomic locations, the extracted locations according to TCGA data, and the quality of used primers and probes for the 11 most studied diagnostic DNA methylation biomarkers in CRC (ALX4, APC, CDKN2A, MGMT, MLH1, NDRG4, SDC2, SFRP1, SFRP2, TFPI2, VIM).
  • how: The authors analyzed the diagnostic CRC methylation biomarkers identified in a previously conducted systematic . . .

     

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