Age-associated gut microbiota impairs hippocampus-dependent memory in vagus-dependent manner

HIGHLIGHTS

  • who: Damien Rei and colleagues from the InstitutCitu00e9 University Animalerie Centrale, Gnotobiology Center, Paris, France have published the paper: Age-associated gut microbiota impairs hippocampus-dependent memory in vagus-dependent manner, in the Journal: Microbiome Medicine (PaCeMM) FHU, Paris, France. of April/30,/2009
  • what: The authors show that fecal microbiota transplantation (FMT) from aged but not young animal donors into young mice is sufficient to trigger profound hippocampal alterations including astrogliosis decreased adult neurogenesis decreased novelty-induced neuronal activation and impairment in hippocampus-dependent memory. The authors report that the transplantation of young (Y . . .

     

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