Drug-loaded pcl electrospun nanofibers as anti-pancreatic cancer drug delivery systems

HIGHLIGHTS

  • who: Oihane Mitxelena-Iribarren from the Polycaprolactone (PCL, Mw=, g/mol), % chloroform, % methanol, % formic acid and, % acetic acid were purchased from Sigma Life Sciences, USA5-Fluorouracil ( F) was purchased from AK Scientific Inc, USA, and Methotrexate (MTX) was kindly provided by Dr. A. Aldaz, from the Department of Pharmacy of Clu00ednica Universidad de Navarra, Spain. Electrospinning of PCL nanofibers Electrospinning solutions were prepared by dissolving , wt.% of PCL in formic acid/acetic acid/chloroform with a ratio of, .5:, .5: , (v/v/v), respectively. The solution was stirred at room temperature overnight and used within the first . . .

     

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