Functional impact of risk gene variants on the autoimmune responses in type 1 diabetes

HIGHLIGHTS

  • who: Chelsea Gootjes from the Laboratory of Immunomodulation and Regenerative Cell Therapy, Department of Internal Medicine, Leiden University Medical United States have published the research: Functional Impact of Risk Gene Variants on the Autoimmune Responses in Type 1 Diabetes, in the Journal: (JOURNAL)
  • what: The authors aim to review the knowledge of functional consequences of T1D risk SNPs on the regulation, expression and function of linked risk genes and further contemplate how this may impact the functionality of the effector vs. regulatory T_cells, changing the balance between immune activation and suppression in the pancreas that . . .

     

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