HIGHLIGHTS
- who: Austin S. Draycott and colleagues from the University, UNITED STATES have published the article: Transcriptome-wide mapping reveals a diverse dihydrouridine landscape including mRNA, in the Journal: (JOURNAL) of July/16,/2021
- what: The authors demonstrate dihydrouridine synthase (DUS)-dependent changes in splicing of a D-containing premRNA in cells and show that D-modified mRNAs can be efficiently translated by eukaryotic ribosomes in vitro. The authors report the development of a novel method to map D residues in RNA in high-throughput. In support of the potential for dihydrouridine to affect mRNA biogenesis . . .
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