Impact of synthesized indoloquinoline analog to isolates from cryptolepis sanguinolenta on tumor growth inhibition and hepatotoxicity in ehrlich solid tumor-bearing female mice

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SUMMARY

Groups Parameters Control APAN ETO APAN+ETO EST EST+APAN EST+ETO EST+APAN+ETO AFP (ng/mL) CEA (ng/mL) Anti-dsDNA (U/mL) Data are presented as mean ± SE, n=8. p and amp;lt; 0.01, (*) indicates a significant difference compared to the control group, and_(**) indicates a significant difference compared to the EST group. The resulting data showed a significant decrease in tumor weight and volume after the treatment by APAN or/and ETO, which may be due to the ability of APAN to intercalate into GC-rich sequences and . . .

 



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