Stylopine: a potential natural metabolite to activate vascular endothelial growth factor receptor 2 (vegfr2) in osteosarcoma therapy

HIGHLIGHTS

  • who: MG- and collaborators from the of Hertfordshire, United Kingdom have published the article: Stylopine: A potential natural metabolite to activate vascular endothelial growth factor receptor 2 (VEGFR2) in osteosarcoma therapy, in the Journal: (JOURNAL)
  • what: In the present study, computer-aided drug design approach involved in a successful screening process of selected chemical library containing 193 benzylisoquinoline alkaloids.
  • how: In this study KEGG database was used for target selection. MTT assay results indicated that the IC50 value of the test compound stylopine and standard axitinib were 0.987 u00b5M and 2.107 . . .

     

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