Association of antihypertensive drugs with fracture and bone mineral density: a comprehensive drug-target mendelian randomization study

HIGHLIGHTS

  • who: Xin Huang and colleagues from the of Bari Aldo Moro, Italy have published the research: Association of antihypertensive drugs with fracture and bone mineral density: A comprehensive drug-target Mendelian randomization study, in the Journal: (JOURNAL)
  • what: In the present study, using single-nucleotide polymorphisms (SNPs) in or near drug_target genes as drug genetic proxies, the authors conducted a comprehensive drug-target MR analysis systematically examining the causal associations between antihypertensive drug classes and bone health-related traits, including fractures, total body bone mineral density (TB-BMD), and estimated heel BMD (eBMD).
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