HIGHLIGHTS
- who: CDG et al. from the United States University of Mu00fcnster, Germany have published the paper: Differential Effects of D-Galactose Supplementation on Golgi Glycosylation Defects in TMEM165 De fi ciency, in the Journal: (JOURNAL)
- what: Although D-Gal supplementation was quite efficient in suppressing the N-glycosylation defects, the authors demonstrate a poor efficiency on O-glycans and a total absence of effects on GAGs, as depicted by the electrophoretic mobility of decorin .
SUMMARY
The biosynthesis of these structures is tightly regulated and defects in any of the glycosylation pathways . . .
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