HIGHLIGHTS
- who: Nicholas J. Hess et al. from the University of Michigan, United States have published the Article: Exosomes, MDSCs and Tregs: A new frontier for GVHD prevention and treatment, in the Journal: (JOURNAL)
SUMMARY
In contrast, induced-Tregs (iTregs) exit the thymus as conventional T_cells but are polarized to iTregs in environments with high levels of TGFb, retinoic acid, IDO, and other mediators. Ongoing studies differ based on their isolation and expansion of tTregs from existing graft material and those that polarize CD4 T_cells in_vitro. Tregs as a GVHD prevention/ treatment modality T . . .
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