Extracellular vesicle-derived mirnas improve stem cell-based therapeutic approaches in muscle wasting conditions

HIGHLIGHTS

  • who: Laura Yedigaryan from the University of Milan, Italy have published the paper: Extracellular vesicle-derived miRNAs improve stem cell-based therapeutic approaches in muscle wasting conditions, in the Journal: (JOURNAL)
  • what: The authors next tested the effects of this set of miRNAs on hMABs: combining mimics and antagomir oligonucleotides, the authors aimed to upregulate and downregulate miR-1, miR-133a, miR-206, and miR-208a using several different combinations of them . 3.5 miRNAs derived from EVs influence the myogenic propensity of target cells Since miRNAs have been heavily implicated in orchestrating myogenesis, the . . .

     

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