HIGHLIGHTS
- who: Ilias Georgakopoulos-Soares from the (UNIVERSITY) have published the Article: Transcription factor binding site orientation and order are major drivers of gene regulatory activity, in the Journal: (JOURNAL)
- what: Using a massively parallel reporter assay (MPRA) of 209,440 sequences, the authors examine all possible pair and triplet combinations, permutations and orientations of eighteen liver-associated transcription factor binding_sites (TFBS). This study provides several important observations on regulatory grammar.
- how: In previous work the authors identified widespread transcriptional strand asymmetries in the orientation of TFBSs across human transcribed regions10 a research area . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.