Coordinated modulation of multiple processes through phase variation of a c-di-gmp phosphodiesterase in clostridioides difficile

HIGHLIGHTS

  • who: Leila M. Reyes Ruiz and collaborators from the Department of Microbiology and Immunology, University of North Carolina School of Medicine, Chapel Hill have published the article: Coordinated modulation of multiple processes through phase variation of a c-di-GMP phosphodiesterase in Clostridioides difficile, in the Journal: (JOURNAL) of June/15,/2022
  • what: The authors aimed to assess whether PdcB phase varies identify the mechanism of regulation and determine the effects on intracellular c-di-GMP levels and regulated phenotypes. The authors show that production of a c-di-GMP hydrolytic enzyme PdcB undergoes phase . . .

     

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