Ppp2ca is a novel therapeutic target in neuroblastoma cells that can be activated by the set inhibitor op449

HIGHLIGHTS

  • who: Celimene Galiger from the Children`s Hospital of Los Angeles, United States University of Catania, Italy have published the article: PPP2CA Is a Novel Therapeutic Target in Neuroblastoma Cells That Can Be Activated by the SET Inhibitor OP449, in the Journal: (JOURNAL)
  • future: Future investigations are warranted to assess the efficacy of OP449 against NB in_vivo.

SUMMARY

    Neuroblastoma (NB) is the most common extracranial solid tumor in childhood. Compared with several other PP2A-reactivating drugs (PADs), the novel SET antagonist OP449 has been shown to be particularly effective and devoid . . .

     

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