Dyrk2 downregulation in colorectal cancer leads to epithelial-mesenchymal transition induction and chemoresistance

HIGHLIGHTS

  • who: Chunrong Wu from the DepartmentChongqing University have published the research: DYRK2 downregulation in colorectal cancer leads to epithelial-mesenchymal transition induction and chemoresistance, in the Journal: Scientific Reports Scientific Reports
  • how: Together these data indicated that DYRK2 downregulation was associated with enhanced malignancy in 5-FUR LoVo cells.

SUMMARY

    CRC patient tissue microarrays (TMAs) were further employed to explore the correlative relationships between the expression of DYRK2 and patient clinicopathological characteristics using an immunohistochemical (IHC) staining approach, revealing that 65.06% (54/83) of the samples in this TMA specimens . . .

     

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