Metformin attenuates slow-to-fast fiber shift and proteolysis markers increase in rat soleus after 7 days of rat hindlimb unloading

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  • who: Kristina A. Sharlo and colleagues from the Institute of Biomedical Problems, RAS, Moscow, Russia have published the paper: Metformin Attenuates Slow-to-Fast Fiber Shift and Proteolysis Markers Increase in Rat Soleus after 7 Days of Rat Hindlimb Unloading, in the Journal: (JOURNAL) of 31/05/2021
  • what: The authors hypothesized that the prevention of downregulation during the first week of muscle would impede atrophy development and the shift of soleus muscle fibers and the aim of the study was test this hypothesis. The beneficial effect of metformin on the percentage of slow-type . . .

     

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