HIGHLIGHTS
- who: Robert A. Saxton from the In vivo studies Animal experiments were performed according to a procedure approved by the Stanford University Administrative Panel on Laboratory Animal Care (APLAC)Mice were maintained in, h light-dark cycles at , u00b0C and ~50% relative humidity and fed a standard irradiated rodent chow diet. Male, .Cg-Lepob/J (stock no., ) were purchased from Jackson Laboratory. Proteins were diluted in sterile PBS and were administered twice a day at , am and , pm via intraperitoneal injection at, ., u03bcL/g body weight at the indicated doses. Mice were mock injected with PBS , days . . .
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