HIGHLIGHTS
- who: Wenxiang Wang and colleagues from the University, Taiwan have published the paper: Pharmacokinetics, bioavailability, and excretion of ponazuril in piglets, in the Journal: (JOURNAL)
- what: This study assessed an unbiased bioavailability using the NLME model, yet the Frontiers in Veterinary Science main shortcoming is the absence of a multi-dose experimental design, which would help to examine the potential non-linear mechanisms of ponazuril more scientifically. Before the present work, few studies have evaluated the oral bioavailability of ponazuril using intravascular administration in these animals, and their pharmacokinetic profiles show varying degrees of interspecies . . .
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