A fret-based respirasome assembly screen identifies spleen tyrosine kinase as a target to improve muscle mitochondrial respiration and exercise performance in mice

HIGHLIGHTS

• who: Ami Kobayashi from the Tokyo Metropolitan Institute of Gerontology (approval no18021). This study complied with ARRIVE guidelines (https://arriveguidelines.org/). have published the paper: A FRET-based respirasome assembly screen identifies spleen tyrosine kinase as a target to improve muscle mitochondrial respiration and exercise performance in mice, in the Journal: (JOURNAL) of 16/05/2022
• what: FRET biosensors of mitochondrial respiratory complexes enable visualization of supercomplex formation in myoblastic cells To develop a FRET-based assay of MRC supercomplex formation, the authors focused on the interaction between respiratory complexes I and IV. This experiment . . .
  

   

  

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