Cst1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating gpx4 protein stability via otub1

HIGHLIGHTS

• who: Dongbao Li from the Tissue specimens Primary GC tissues and the corresponding non-cancerous adjacent tissues were collected from , patients who underwent gastric resection for GC without neoadjuvant therapy at the First Affiliated Hospital of Soochow University from , and Ninety-five GC patients completed followup and underwent clinicopathological and prognostic analysis. Among them, pairs of primary GC and adjacent normal tissues without metastasis, and , pairs of primary GC and adjacent normal tissues with peritoneal metastasis were used for whole transcriptome sequencing (OE Biotech, Shanghai, China). The remaining samples were stored at , u00b0C for RT-qPCR or . . .
  

   

  

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