Synthesis and in silico docking study towards m-pro of novel heterocyclic compounds derived from pyrazolopyrimidinone as putative sars-cov-2 inhibitors

HIGHLIGHTS

  • who: Mabrouk Horchani and collaborators from the Laboratory of Heterocyclic Chemistry, Natural and Reactivity, Medicinal Chemistry and Natural (LR ES39), Faculty of Sciences of Monastir, University of Monastir, Monastir, Tunisia , Halle, Germany have published the article: Synthesis and In Silico Docking Study towards M-Pro of Novel Heterocyclic Compounds Derived from Pyrazolopyrimidinone as Putative SARS-CoV-2 Inhibitors, in the Journal: Molecules 2022, x of 26/Nov/2021
  • what: In this study in the search for therapeutic alternatives to treat COVID-19 and its recent variants the authors conducted a structurebased virtual screening using docking . . .

     

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