A positive feedback loop between gastric cancer cells and tumor-associated macrophage induces malignancy progression

HIGHLIGHTS

• who: Haiyan Piao from the (Cancer Hospital of China Medical University), No, Xiaoheyan Road, Dadong have published the article: A positive feedback loop between gastric cancer cells and tumor-associated macrophage induces malignancy progression, in the Journal: (JOURNAL) of December/31,/2020
• what: Our work identifies a hypoxic-activated, inflammation-associated molecular network; which involve CXCL8, CXCR1/2, JAK/STAT1, IL-10, and NF-u03baB signaling pathways that regulate a positive feedback loop between GC cells and TAMs, tumor progression, macrophage polarization, as well as patient outcomes (Fig 7).
• how: The flow cytometry . . .
  

   

  

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