Functional analysis of differently expressed ferroptosis-related genes in patients with mitral valve prolapse

HIGHLIGHTS

  • who: . and collaborators from the Istanbul University, Turkey have published the Article: Functional analysis of differently expressed ferroptosis-related genes in patients with mitral valve prolapse, in the Journal: (JOURNAL)
  • what: CDKN2A, SLC1A4, and ATF3 genes modulate the pathogenesis of MVP.
  • how: Eventually the DESeq2 software fitted the model of the negative binomial distribution and used the Wald test or likelihood ratio test for hypothesis testing. GO analysis results showed that extracellular matrix deposition specifically collagen fiber is a key pathogenic mechanism of MVP.

SUMMARY

    Healthy group. Previous studies . . .

     

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