HIGHLIGHTS
- who: Youying Tu and collaborators from the APP/, mouse is a well-established and widely used double transgenic model of AD [36]Thirty male APP/, (APPswe, PSEN1dE9) adult mice (, months) with a C BL/ J background and six male C BL/ J adult mice were purchased from Shanghai Model Organisms Centre (Shanghai, China). All mice were housed under controlled standard barrier conditions (temperature , u00b1 , u25e6 C, humidity, % u00b1, and , h light-dark cycle) at the Animal Centre of Zhejiang Chinese Medical University. After acclimatization for , week, mice were grouped and treated as follows: negative control (NC), C . . .
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