Mfn2 is responsible for inhibition of the rig-i/irf7 pathway and activation of nlrp3 inflammasome in seneca valley virus-infected pk-15 cells to promote viral replication

HIGHLIGHTS

  • who: HuiDan Deng from the Wistar Institute, United States University of Science and Technology have published the research work: Mfn2 is responsible for inhibition of the RIG-I/IRF7 pathway and activation of NLRP3 inflammasome in Seneca Valley virus-infected PK-15 cells to promote viral replication, in the Journal: (JOURNAL)
  • what: The study demonstrated that Mfn2 inhibited antiviral activity against SVV infection in PK-15 cells.
  • how: Unpaired T-test and One-way analysis of variance (ANOVA) were used to investigate the significance of differences between the experimental groups and the control . . .

     

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