Empagliflozin suppressed cardiac fibrogenesis through sodium-hydrogen exchanger inhibition and modulation of the calcium homeostasis

HIGHLIGHTS

  • who: Cheng-Chih Chung from the Division of Cardiology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan have published the article: Empagliflozin suppressed cardiac fibrogenesis through sodium-hydrogen exchanger inhibition and modulation of the calcium homeostasis, in the Journal: (JOURNAL)
  • what: This study investigated whether SGLT2i directly moduu2011 lates fibroblast activities and its underlying mechanisms.

SUMMARY

    After the intracellular ­Ca2+ surge from the thapsigargin-induced ER ­Ca2+ leak returned to a steady_state, the extracellular ­Ca2+ concentration was increased to 2 mmol/L to measure . . .

     

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