HIGHLIGHTS
- who: Simon Lecoutre and collaborators from the Department of Medicine (H7), Karolinska Institutet Hospital, , Stockholm, SwedenHospital, Paris, France have published the article: Importance of the Microenvironment and Mechanosensing in Adipose Tissue Biology, in the Journal: Cells 2022, 11, 2310. of /2022/
- what: This study reported that Yap overexpression in ASC induced a negative_feedback mechanism on the Hippo signaling pathway, leading to suppression of TAZ activity.
SUMMARY
In obesity, white adipose_tissue (WAT) can expand by 10 times through hypertrophy (enlarged adipocyte size) and hyperplasia (increased adipocyte number), whereas upon fasting or cold . . .
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