Computer-aided directed evolution generates novel aav variants with high transduction efficiency

HIGHLIGHTS

  • who: Zengpeng Han and colleagues from the State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Key Laboratory of Magnetic Measurement Science and Technology, Chinese Academy of Sciences, Wuhan, China University of Chinese Academy of Sciences, Beijing, China have published the Article: Computer-Aided Directed Evolution Generates Novel AAV Variants with High Transduction Efficiency, in the Journal: Viruses 2023, 15, 848. of 26/03/2023
  • what: The authors generated 95,995 sequences that the models rated as could be assembled; among them, about 1/3 were generated with random multi-mutation, 1/3 . . .

     

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