The ral enigma: distinct roles of rala and ralb in cancer

HIGHLIGHTS

  • who: Dillon S. Richardson and collaborators from the The Ohio State University Comprehensive Cancer Center-James Cancer Hospital and Solove Research Institute have published the paper: The RAL Enigma: Distinct Roles of RALA and RALB in Cancer, in the Journal: Cells 2022, 1645 of /2022/
  • what: In this review the authors examine the functions of the paralogs in normal cellular physiology and cancer biology with special consideration provided to situations where the roles of and are non-redundant. These AML studies, like the previously described CML studies, focused on only one RAL paralog.
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