Establishment of a novel method to assess mek1/2 inhibition in pbmcs for clinical drug development

HIGHLIGHTS

  • who: Methods and colleagues from the Institute of Biomedicine and Spain University of Bradford, United Kingdom have published the Article: Establishment of a novel method to assess MEK1/2 inhibition in PBMCs for clinical drug development, in the Journal: (JOURNAL)
  • what: As a next step, the authors aimed to compare ERK1/2 phosphorylation measured either by the Wes or the MSD system.

SUMMARY

    The Raf/MEK/ERK signaling cascade is one of the crucial pathways for transmission of extracellular signals from neurotransmitters, growth factors, hormones, or other stimuli in the cell . . .

     

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